Manifestations of Alveolar Proteinosis: Case Description and Literature Review
Abstract
Pulmonary alveolar proteinosis (PAP) is a rare disease that diffusely compromises the pulmonary interstitium with accumulation of pulmonary surfactant and alveolar obstruction resulting in respiratory failure. The following case report describe a 32- year-old male patient resident in Bogota, Colombia who was hospitalized due to progressive deterioration in functional class requiring supplemental oxygen, the admission physical examination findings are consistent with bibasal fine rales associated with clubbing, a chest computed tomography (CT) was performed showing “crazy paving” pattern, the cytological exam revealed plenty proteic content associated with PAS (+) macrophages , for this reason the diagnosis of PAP was made and whole lung lavage was performed presenting oxygenation improvement being able to discharged the patient from hospital care. Due to the lack of studies in Colombia that report PAP, the present article seeks to discuss clinical findings along with the diagnostic and treatment given to this patient.
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