Radiocirugía en glioblastoma: una revisión de la literatura
Resumen
El manejo de gliomas de alto grado, particularmente el glioblastoma, sigue siendo desafiante a pesar de los avances en la terapia de radiación y la cirugía. El cuidado estándar implica una resección quirúrgica máxima, seguida de radioterapia y quimioterapia con Temozolomida. La Radiocirugía Estereotáctica con Gamma Knife (GKRS) ha surgido como una opción no invasiva y efectiva para tratar una variedad de lesiones del sistema nervioso central. La GKRS ofrece una entrega precisa de radiación de baja energía a un objetivo definido, induciendo la destrucción del tejido mientras preserva el tejido cerebral sano. Aunque se han observado efectos secundarios como la necrosis por radiación, la GKRS muestra promesas en el tratamiento del glioblastoma, incluso con su naturaleza infiltrativa. Esta revisión explora el panorama evolutivo del manejo de gliomas de alto grado, centrándose en el potencial de la GKRS para mejorar los resultados del tratamiento.
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