Streptococcus agalactiae y susceptibilidad en gestantes de un hospital en Palmira, Valle
Resumen
Streptococcus agalactiae o estreptococo del grupo B es un coco grampositivo, saprofito, colonizador del tracto gastrointestinal y genitourinario que causa infecciones fundamentalmente en recién nacidos, embarazadas y en raras ocasiones en adultos con enfermedades de base. La portación de este microorganismo puede ser causa importante de corioamnionitis y endometritis posparto. Se describirá la susceptibilidad de S. agalactiae en gestantes que asistieron al servicio de obstetricia en un hospital nivel II de Palmira entre el primero de enero de 2018 y el 31 de diciembre de 2019, mediante un estudio descriptivo retrospectivo. Se obtuvieron 58 cultivos rectovaginales positivos para S. agalactiae mediante hisopado vaginal y rectal, datos suministrados por el laboratorio del Hospital Raúl Orejuela Bueno. La prueba de susceptibilidad antimicrobiana se realizó utilizando el método automatizado VITEK-2. En los 58 cultivos rectovaginales positivos para Streptococcus agalactiae se observó una sensibilidad del 100 % a la ampicilina, levofloxacino y moxifloxacino; 98 % a la quinupristina, linezolid y vancomicina sensible.
Descargas
Referencias bibliográficas
Delgado-Arévalo KJ, González-Habib R. Tamizaje del estreptococo del grupo B durante el embarazo: conducta actual en un centro de tercer nivel. Ginecol Obstet Mex. 2020;88(02):127-129. https://doi.org/10.24245/gom.v88i2.3716
do Nascimento, CS et al. Streptococcus Agalactiae in Pregnant Women in Brazil: Prevalence, Serotypes, and Antibiotic Resistance. Braz J Microbiol. 2019 Feb;50: 943-952. https://doi.org/10.1007/s42770-019-00129-8
Baron Barshak M, Madoff Lawrence C. Group B Streptococcal Infections in Nonpregnant Adults. UpToDate;2022, Disponible en: https://www.uptodate.com/contents/group-b-streptococcal-infections-in-nonpregnant-adults?search=stre
Poupolo KM, Madoff LC. Group B Streptococcal Infection in Pregnant Individuals. UpToDate;2022. Disponible en: https://www.uptodate.com/contents/group-b-streptococcal-infection-in-pregnant-individuals?search=s%20treptococcus%20agalactiae&source=search_result&selectedTitle=2~150&usage_type=default&display_rank=2
Madoff LC. Estreptococo del grupo B: factores de virulencia y mecanismos patogénicos. UpToDate;2022.Disponible en:https://www.uptodate.com/contents/group-b-streptococcus-virulence-factors-and-pathogenic-mechanisms?search=streptococcus%20agalactiae&source=search_result&selectedTitle=5~150&usage_type=default&display_rank=5
Baker CJ. Prevention of Early-Onset Group B Streptococcal Disease in Neonates, UpToDate; 2022. Disponible en: https://www.uptodate.com/contents/prevention-of-early-onset-group-b-streptococcal-disease-in-neonates?search=streptococcus%20agalactiae&source=search_result&selectedTitle=4~150&usage_type=default&display_rank=4
Poupolo KM, Baker CJ. Management of Neonates at Risk for Early-Onset Group B Streptococcal Infection.UpToDate; 2022. https://www.uptodate.com/contents/management-of-neonates-at-risk-for-early-onset-group-b-streptococcal-infection
Rajack F, et al. An Emerging Infection: Streptococcal Toxic Shock-Like Syndrome Caused by Group B Streptococcus (GBS), Streptococcus Agalactiae. American Journal of Clinical Pathology. 2020;154(1):S140. https://doi.org/10.1093/ajcp/aqaa161.306
Furfaro LL, Chang Barbara J. Perinatal Streptococcus agalactiae Epidemiology and Surveillance Targets. Clin Microbiol Rev. 2018 Ago 15;31(4):e00049-18. https://doi.org/10.1128/CMR.00049-18
Lopardo, HÁ, Berardinelli EM. Estreptococos del grupo Streptococcus anginosus Parte II. Patogenia y sensibilidad a los antibióticos. Acta Bioquímica Clínica Latinoamericana. 2021;55(1):61-77. Disponible en: https://www.redalyc.org/journal/535/53566167011/html/
Duarte C, et al. Streptococcus Pneumoniae Serotype 3 Genotypes in Invasive Isolates from Colombia. Biomédica. 2021 Jun 29;41(2):338-346. https://doi.org/10.7705/biomedica.5407
Renato de Ávila K; Pignatari, Antônio Carlos Campos, Capsular genotype distribution of Group B Streptococcus colonization among at-risk pregnant women in Sao Paulo, Brazil. Braz J Infect Dis. 2021 May-Jun;25(3):101586. https://doi.org/10.1016/jbjid.2021.101586
Verani JR, et al. Prevention of Perinatal Group B Streptococcal Disease Revised Guidelines from CDC.MMWR Recomm Rep. 2010 Nov 19;59(RR-10):1-36.PMID: 21088663
Melo SCCS de, et al. Prevalence of Streptococcus agalactiae Colonization in Pregnant Women from the 18th Health Region of Paraná State. Rev. Inst.Med. trop. 2018;60:e2. https://doi.org/10.1590/S1678-9946201860002
Gizachew M, et al. Streptococcus agalactiae from Ethiopian Pregnant Women; Prevalence, Associated Factors and Antimicrobial Resistance: Alarming for Prophylaxis. Ann Clin Microbiol Antimicrob. 2019;18(3):1-9. https://doi.org/10.1186/s12941-019-0303-3
Committee Opinion, Early-Onset Group B Streptococcal Disease. Obstet Gynecol. 2020 Feb;135(2):e51-e72.17. Edwards MS, Baker CJ. Streptococcus agalactiae (Group B Streptococcus). En GL Mandell, JE Bennett, R Dolin. (eds.). Principles & Practice of Infectious Diseases. Vol. 2, 7a. ed. Filadelfia: Elsevier; 2010. p. 2655-66. Chapter 202.
Edwards MS, Nizet V. Group B streptococcal infections. En: JS Remington, JO Klein, CB Wilson, V Nizet V, YA Maldonado YA. (eds.). Infectious Diseases of the Fetus and Newborn Infant. 7a. ed. Filadelfia: Elsevier;2011. p. 419-69.
Verani JR, Schrag SJ. Group B Streptococcal Disease in Infants: Progress in Prevention and Continued Challenges. Clin Perinatol. 2010 Jun;37(2):375-92. https://doi.org/10.1016/j.clp.2010.02.002
Stoll BJ, et al. Early Onset Neonatal Sepsis: The Burden of Group B Streptococcal and E. Coli Disease Continues. Pediatrics. 2011;127(5):817-26. https://doi.org/10.1542/peds.2010-2217
Herbert MA, Beveridge CJE, Saunders NJ. Bacterial virulence factors in neonatal sepsis: group B Streptococcus.Curr Opin Infect Dis. 2004 Jun;17(3):225-9.https://do.org/10.1097/00001432-200406000-00009
Burnham CA, Tyrrell GJ. Virulence factors of group B streptococci. Rev. Med Microbiol 2003;14:109-18. https://doi.org/10.1097/00013542-200310000-00002
Le Doare K, Heath P. An overview of global GBS epidemiology.Vaccine. 2013 Aug 28;31 Suppl 4:D7-12.https://doi.org/10.1016/j.vaccine.2013.01.009
Schrag S. Prevention of Perinatal Group B Streptococcal Disease. Revised Guidelines from CDC. MMWR Recomm Rep. 2002 Ago 16;51(RR-11):1-22. PMID:12211284
De Mouy D, et al. AFICORPI-BIO Network. Antibiotic Susceptibility and Mechanisms of Erythromycin Resistance in Clinical Isolates of Streptococcus agalactiae:French Multicenter Study. Antimicrob Agents Chemother. 2001 Ago;45(8):2400-2. https://doi.org/10.1128/AAC.45.8.2400-2402.2001
Uh Y, et al. Emerging Erythromycin Resistance among Group B Streptococci in Korea. Eur J Clin Microbiol Infect Dis. 2001 Ene;20(1):52-4. https://doi. org/10.1007/s100960000414
Schrag S, et al. Prevention of Perinatal Group B Streptococcal Disease Revised Guidelines from CDC.MMWR Recomm Rep 2002 Ago 16;51(RR-11):1-22.PMID: 12211284
Chiao WL, et al. Serotype Distribution and Clinical Correlation of Streptococcus agalactiae Causing Invasive Disease in Infants and Children in Taiwan. Journal of Microbiology, Immunology and Infection. 2019 Ago;52(4):578-584. https://doi.org/10.1016/j.jmii.2017.09.002
Weisner AM, et al. Characterization of group B streptococci Recovered from Infants with Invasive Disease in England and Wales. Clin Infect Dis. 2004 May 1;38(9):1203-8. https://doi.org/10.1086/382881
Zaleznik DF, et al. Invasive Disease due to Group B Streptococcus in Pregnant Women and Neonates from Diverse Population Groups. Clin Infect Dis. 2000 Feb;30(2):276-81. https://doi.org/10.1086/313665
Hooven TA, et al. The Streptococcus agalactiae Stringent Response Enhances Virulence and Persistence in Human Blood. ASM Journals Infection and Immunity, 2018;86(1): https://doi.org/10.1128/IAI.00612-17
Martínez Sánchez LM, et al. Prevención de la infección por Streptococcus del grupo B. Med UNAB. 2017 Ago-Nov;20(2):182-189. https://doi.org/10.29375/01237047.2308
Sociedad Latinoamericana de Infectología Pediátrica. Opinión de expertos sobre Infecciones Congénitas y Perinatales (ICP) SLIPE‐2014. Disponible en: http://www.slipe.org/informesAcademicos.asp
Verani JR, et al. Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention (CDC). Prevention of Perinatal Group B Streptococcal Disease--Revised Guidelines from CDC, 2010.MMWR Recomm Rep. 2010 Nov 19;59(RR-10):1-36.PMID: 21088663
Pannaraj PS, Baker CJ. Group B Streptococcal Infections. En: JD Cherry, WJ Steinbach, GJ Harrison, et al.(eds.). Feigin and Cherry’s Textbook of Pediatric Infectious Diseases. 7th ed. Filadelfia: Elsevier Saunders;2014. p. 1153-69.
Palacios Saucedo GC, et al. Infección perinatal por estreptococo del grupo B: Panorama global, en América Latina y en México. Gac Med Mex. 2017;153(3):361-370. Disponible en: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=74777
Villaseñor-Sierra A, et al.Prevalencia de Streptococcus agalactiae del serotipo III en embarazadas.Ginecol Obstet Mex.2004;72:103-8.Disponible en:https://ginecologiayobstetricia.org.mx/articulo/prevalencia-de-streptococcus-agalactiae-del-serotipo-iii-en-embarazadas
Faro J. More Rapid Testing Group B Streptococcus Detection.MLO Med Lab Obs. 2013 Jun;45(6):15. PMID:23875438 39. Park JS, et al. Usefulness of a Rapid Real-Time PCR Assay in Prenatal Screening for Group B Streptococcus Colonization. Ann Lab Med. 2013 Ene;33(1):39-44.https://doi.org/10.3343/alm.2013.33.1.39
Yancey MK, et al. The Accuracy of Late Antenatal Screening Cultures in Predicting Genital Group B Streptococcal Colonization at Delivery. Obstet Gynecol. 1996 Nov;88(5):811-5. https://doi.org/10.1016/0029-7844(96)00320-1
Alós Cortés JI, et al. Prevención de la infección perinatal por estreptococo del grupo B. Recomendaciones españolas. Actualización 2012. Documento de consenso SEIMC/SEGO/SEN/SEQ/SEMFYC. Enferm Infecc Microbiol Clin. 2013;31(3):159-172. https://doi.org/10.1016/j.eimc.2012.03.013
Fay K, et al. Antenatal and Intrapartum Nucleic Acid Amplification Test use for Group B Streptococcus Screening United States, 2016. Diagn Microbiol Infect Dis. 2019 Jun;94(2):157-159. https://doi.org/10.1016/j.diagmicrobio.2018.11.026
Melin P. Neonatal Group B Streptococcal Disease:from Pathogenesis to Preventive Strategies. Clin Microbio Infect. 2011 Sep;17(9):1294-303. https://doi.org/10.1111/j.1469-0691.2011.03576.x
Kimura K, et al. Active Screening of Group B Streptococci with Reduced Penicillin Susceptibility and Altered Serotype Distribution Isolated from Pregnant Women in Kobe, Japan. Jpn J Infect Dis. 2013;66(2):158-60 https://doi.org/10.7883/yoken.66.158
Capanna F, et al. Antibiotic Resistance Patterns among Group B Streptococcus Isolates: Implications for Antibiotic Prophylaxis for Early-Onset Neonatal Sepsis.Swiss Med Wkly. 2013 Mar 25;143:w13778. https://doi.org/10.4414/smw.2013.13778
Nanduri SA, et al. Epidemiology of Invasive Early-Onset and Late-Onset Group B Streptococcal Disease in the United States, 2006 to 2015: Multistate Laboratory and Population-Based Surveillance [preprint]. JAMA Pediatr. 2019 Mar 1;173(3):224-233. https://doi.org/10.1001/jamapediatrics.2018.4826
Creti R, et al. Italian Neonatal GBS Infections Working Group. Neonatal Group B Streptococcus Infections: Prevention Strategies, Clinical and Microbiologic Characteristics in 7 Years of Surveillance. Pediatr Infect Dis J. 2017 Mar;36(3):256-262. https://doi.org/10.1097/INF.0000000000001414
Castor ML, et al. Antibiotic Resistance Patterns in Invasive Group B Streptococcal Isolates. Infect Dis Obstet Gynecol. 2008;2008:727505. https//:doi.org/10.1155/2008/727505
Teatero S, et al. Serotype Distribution, Population Structure, and Antimicrobial Resistance of Group B Streptococcus Strains Recovered from Colonized Pregnant Women. J Clin Microbiol. 2017 Feb;55(2):412-422. https://doi.org/10.1128/JCM.01615-16
Bulska M, et al. The Placental Transfer of Erythromycin in Human Pregnancies with Group B Streptococcal Infection. Ginekol Pol. 2015 Ene;86(1):33-9. https://doi.org/10.17772/gp/1896
Salkind AR, et al. The Rational Clinical Examination. Is this Patient Allergic to Penicillin? An Evidence-Based Analysis of the Likelihood of Penicillin Allergy.JAMA. 2001 May 16;285(19):2498-505. https://doi.org/10.1001/jama.285.19.2498
Joint Task Force on Practice Parameters; American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma and Immunology; Joint Council of Allergy, Asthma and Immunology.Drug allergy: an updated practice parameter.Ann Allergy Asthma Immunol. 2010 Oct;105(4):259-273.https://doi.org/10.1016/j.anai.2010.08.002
Macy E, Vyles D. Who needs penicillin allergy testing? Ann Allergy Asthma Immunol. 2018 Nov;121(5):523-529. https://doi.org/10.1016/j.anai.2018.07.041
Melin P, Efstratiou A. Group B streptococcal epidemiology and vaccine needs in developed countries.Vaccine.2013; 28; 31 Suppl 4:D31-42. Disponible en:http://goo.gl/hGvBTZ
Stylianopoulos A, et al. Is Penicillin and/or Erythromycin Resistance Present in Clinical Isolates of Group B Streptococcus in our Community? Aust N Z J Obstet Gynaecol. 2002 Nov;42(5):543-4. https://doi.org/10.1111/j.0004-8666.2002.00543.x
Martín V, et al. Rectal and Vaginal Eradication of Streptococcus agalactiae (GBS) in Pregnant Women by Using Lactobacillus salivarius CECT 9145. A Target Target-specific Probiotic Strain. Nutrients. 2019;11(4):810.https://doi.org/10.3390/nu11040810
Fernandez M, et al. Antimicrobial Susceptibilities of Group B Streptococci Isolated between 1992 and 1996 from Patients with Bacteremia or Meningitis. Antimicrob Agents Chemother. 1998 Jun;42(6):1517-9.https://doi.org/10.1128/AAC.42.6.1517
Pearlman MD, et al. Frequent Resistance of Clinical Group B Streptococci Isolates to Clindamycin and Erythromycin. Obstet Gynecol. 1998 Ago;92(2):258-61. https://doi.org/10.1016/s0029-7844(98)00155-0
González-Lama Z, et al. Sensibilidad de estreptococo beta hemolítico grupos A, B y C a antibióticos. Rev Esp Quimioter. 1999;12(3):215-19.
Takahashi T, et al. Clonal Distribution of Clindamycin-Resistant Erythromycin-Susceptible (CRES) Streptococcus agalactiae in Korea Based on Whole Genome Sequences. Ann Lab Med. 2020;40(5):370-381.https://doi.org/10.3343/alm.2020.40.5.37
Betriu C, et al. Erythromycin and Clindamycin Resistance and Telithromycin Susceptibility in Streptococcus agalactiae. Antimicrob Agents Chemother. 2003;47(3):1112-14. https://doi.org/10.1128/AAC.47.3.1112-1114.2003
Schrag S, et al. Prevention of Perinatal Group B Streptococcal Disease Revised Guidelines from CDC.MMWR Recomm Rep 2002 Ago 16;51(RR-11):1-22.PMID: 12211284
Sociedad Española de Ginecología y Obstetricia (SEGO). Sociedad Española de Neonatología (SEN).Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica (SEIMC). Sociedad Española de Quimioterapia (SEQ). Sociedad Española de Medicina Familiar y Comunitaria (SEMFYC). Prevención de la infección perinatal por estreptococo del grupo B. Recomendaciones españolas revisadas. Enferm Infecc Microbiol Clin 2003;21:417-23.
Lin FYC, et al. Antibiotic Susceptibility Profiles for Group B Streptococci Isolated from Neonates, 1995-1998. Clin Infect Dis 2000;31(1):76-9. https://doi.org/10.1086/313936
Fitoussi F, et al. Mechanisms of Macrolide Resistance in clinical Group B Streptococci Isolated in France. Antimicrob Agents Chemother. 2001 Jun;45(6):1889-91. https://doi.org/10.1128/AAC.45.6.1889-1891.2001
Ko WC, et al. Serotyping and Antimicrobial Susceptibility of Group B Streptococcus over an Eight Years Period in Southern Taiwan. Eur J Clin Microbiol Infect Dis. 2001 May;20(5):334-9. https://doi.org/10.1007/s100960100505
Morales WJ, et al. Change in Antibiotic Resistance of Group B Streptococcus: Impact on Intrapartum Management.Am J Obstet Gynecol. 1999 Ago;181(2):310-4. https://doi.org/10.1016/s0002-9378(99)70553-3
Murdoch DR, Reller B. Antimicrobial Susceptibilities of group B Streptococci Isolated from Patients with Invasive Disease: 10 years Perspective. Antimicrob Agents Chemother. 2001 Dic;45(12):3623-4. https://doi.org/10.1128/AAC.45.12.3623-3624.2001
Johnson, M.Clindamicina: una descripción general. UpToDate; 2022.Disponible en: https://www.uptodate.com/contents/clindamycin-an-overview?-search=streptococcus%20agalactiae&source=search_result&selectedTitle=22~150&usage_type=default&-display_rank=22
Ardanuy C, et al. Detección fenotípica de mecanismos de resistencia en grampositivos. Enferm Infecc Microbiol Clin. 2012 Jun-Jul;30(6):325-32. https://doi.org/10.1016/j.eimc.2011.09.009
Díaz M, et al. Infección por estreptococo del grupo B en niños después del período neonatal. Rev Cubana Pediatr 2006 Dic;78(4). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75312006000400001&lng=es
Crespo MP, et al. Importancia clínica del Streptococcus agalactiae como causante de infección.Colomb Med 1996;27(2):53-8. Disponible en: https://colombiamedica.univalle.edu.co/index.php/comedica/article/view/19
Campo CH, et al. Prevalencia de colonización vaginorrectal por Streptococcus agalactiae y su perfil de sensibilidad en mujeres embarazadas atendidas en un hospital de tercer nivel. Biomédica. 2019 Dic;39(4):689-698.http://dx.doi.org/10.7705/biomedica.4514
Kimura K. Series of Studies Concerning Group B Streptococci with Reduced Penicillin Susceptibility (PRGBS). Nihon Saikingaku Zasshi. 2014;69:547-55.https://doi.org/10.3412/jsb.69.547
Derechos de autor 2023 Revista Med
Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0.
.png)
